2005 Congress Abstracts

Abstracts 2005

A TRUNCATED FORM OF HEME OXYGENASE-1 IS FOUND IN THE NUCLEUS OF CULTURED CELLS IN RESPONSE TO INCREASES IN INTRACELLULAR HEME

Guang Yang, Ph.D.*, Qing Lin, Ph.D.*, Yi-Hao Weng, M.D.#. Kimberly Rish, M.S.**, Ann Smith, Ph.D. ** and Phyllis A. Dennery, M.D.

*†#.Children's Hospital of Philadelphia*, Department of Pediatrics, University of Pennsylvania†, Philadelphia, Pennsylvania; School of Biological Sciences, University of Missouri-Kansas City**, Kansas City, Missouri; and Department of Pediatrics, Stanford University#, California, U.S.A.

ACTIVE SITE OF HUMAN FERROCHELATASE

H.A. Dailey, C.-K. Wu, W.N. Missaoui, P. Horanyi, B.-C. Wang, J. Rose, and T.A. Dailey

Biomedical and Health Sciences Institute, Department of Microbiology, and Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602

ALA-PDT SENSITIVITY OF CELL LINES RESISTANT TO NITRIC OXIDE CYTOTOXICITY

Gabriela Divenosa, Adriana Casas, Christian Perotti, Haydee Fukuda & Alcira Batlle

Centro de Investigaciones dsbre Porfirinas y Porfirias (CIPYP), CONICET and University of Buenos Aires

In an attempt to elucidate interactions between aminolevulinic acid-based photodynamic therapy (ALA-PDT) and nitric oxide (NO) cytotoxicity, we employed a murine mammary adenocarcinoma cell line LM3 and the NO resistant variant LM3-SNP.

ATYPICAL RED CELL INCLUSIONS IN A PATIENT WITH CONGENITAL ERYTHROPOIETIC PORPHYRIA

A Merino, M Rozman*, C Herrero**, J To-Figueras, A Ordinas

Servicio de Hemoterapia-Hemostasia. Core Lab. *Unidad de Hematopatología. CDB.**ICMD. Hospital Clínic. IDIBAPS. Universidad de Barcelona

We show the morphological finding of some atypical inclusions in mature red cells and their precursors in a 28 years-old patient with congenital erythropoietic porphyria.

BIOCHEMICAL AND GENETIC CHARACTERIZATION OF FOUR CASES OF HEREDITARY COPROPORPHYRIA IN SPAIN

Carmen Herrero , Jordi To-Figueras , Celia Badenas , Maria T Enríquez (*), Sonia Segura , Concepción Alvarez (**), Montserrat Milà , Marius Lecha

Porphyria , Dermatology and Genetics Unit. Hospital Clínic. University of Barcelona. Villarroel 170. 08036 Barcelona. Spain; (*): Pediatrics Service. Hospital Axarquia. Malaga; (**): Hospital Marques de Valdecilla. Santander. Spain

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